Zu "607378-18-7" wurden 2 Artikel gefunden!
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AZ10606120 dihydrochloride
Artikelnummer: TGM-T14366-10mg
Description: AZ10606120 dihydrochloride is a selectable, potent, high-affinity receptor antagonist with K D values of 1.4 and 19 nM at human and rat P2X 7 receptors, respectively. AZ10606120 dihydrochloride inhibits tumor growth and has anti-angiogenic activity. AZ 10606120 acts as a negative allosteric modulator...
| Anwendung: | P2X7 receptor antagonist |
| CAS | 607378-18-7 |
| MW: | 495.48 D |
ab 60,00 €
AZ 10606120 (hydrochloride)
Artikelnummer: Cay35820-1
AZ 10606120 is an antagonist of the purinergic P2X7 receptor (IC50 = 10 nM). It reduces cell migration and proliferation of PANC-1 pancreatic ductal adenocarcinoma cells when used at a concentration of 10 µM. AZ 10606120 (0.01 µg/kg) reduces cecal slurry-induced impairment of endothelial-dependent relaxation but...
| Schlagworte: | N-[2-[[2-[(2-hydroxyethyl)amino]ethyl]amino]-5-quinolinyl]-tricyclo[3.3.1.13,7]decane-1-acetamide, dihydrochloride |
| Anwendung: | P2X7 receptor antagonist |
| CAS | 607378-18-7 |
| MW: | 495.5 D |
ab 116,00 €
