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Amrinone
Artikelnummer: Cay23898-250
Amrinone is an inhibitor of phosphodiesterase 3 (PDE3, IC50 = 19.5 µM). It increases developed tension and contractile force in isolated cat papillary muscle. Amrinone (1-10 mg/kg) has positive inotropic effects, increasing the rate and force of heart contraction in anesthetized and unanesthetized dogs.Formal Name:...
| Schlagworte: | WIN 40,680, 5-amino-[3,4'-bipyridin]-6(1H)-one |
| Anwendung: | PDE3 inhibitor |
| CAS | 60719-84-8 |
| MW: | 187.2 D |
ab 60,00 €
Amrinone
Artikelnummer: LKT-A5170.250
White to off-white powder. Selective phosphodiesterase III inhibitor. A nonglycoside, noncatecholamine agent with positive inotropic effect. Inhibits cyclic AMP-dependent protein kinase activity by competing with ATP but not cyclic AMP binding sites. It also inhibits platelet aggregation and induces disaggregation.
| Schlagworte: | Cartonic, Inocor, Vesistol, Wincoram |
| Anwendung: | Phosphodiesterase PDE3 inhibitor |
| CAS | 60719-84-8 |
| MW: | 187,2 D |
ab 121,00 €
