Zu "606143-52-6" wurden 4 Artikel gefunden!
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AZD 6244
Artikelnummer: Cay11599-10
MEK kinases are central components of diverse intracellular signaling pathways. MEK1 and MEK2 specifically act downstream of growth factor receptors and the proto-oncogenes Ras and Raf to activate ERK1 and ERK2, often leading to an increase in cell proliferation. AZD 6244 is a potent, highly selective inhibitor of...
| Schlagworte: | ARRY-142886, CL 1,040, NSC 741O78, Selumetinib,... |
| Anwendung: | MEK1 / MEK2 inhibitor |
| CAS | 606143-52-6 |
| MW: | 457.7 D |
ab 43,00 €
Selumetinib
Artikelnummer: LKT-S1846.1
Selumetinib is a selective inhibitor of MEK1/2. Selumetinib treatment induced G1 cell-cycle arrest and apoptosis and suppression of tumor growth as xenografts in immunodeficient mice.
| Schlagworte: | AZD6244, ARRY 142886 |
| CAS | 606143-52-6 |
| MW: | 457.68 D |
ab 77,00 €
Selumetinib, Free Base (AZD6244, ARRY-142886, ARRY-886,...
Artikelnummer: LC-S-4490_1g
Soluble in DMSO
| Schlagworte: | ARRY-142886, CL 1,040, NSC 741O78, Selumetinib,... |
| Anwendung: | MEK1 / MEK2 inhibitor |
| CAS | 606143-52-6 |
| MW: | 457,68 D |
ab 79,00 €
Selumetinib
Artikelnummer: AG-CR1-3757-M010
Appearance: White to off-white solid. Solubility: Soluble in DMSO (100mg/ml). Soluble in ethanol (~1mg/ml with warming). Insoluble in water. InChi Key: CYOHGALHFOKKQC-UHFFFAOYSA-N Smiles: Cn1cnc2c1cc(c(c2F)Nc3ccc(cc3Cl)Br)C(=O)NOCCO Selumetinib is an orally available, potent and selective ATP non-competitive...
| Schlagworte: | AZD6244, ARRY-142886, CL 1,040, NSC741O78 |
| Anwendung: | MEK1 inhibitor |
| CAS | 606143-52-6 |
| MW: | 457.7 D |
ab 28,00 €
