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P-1075
Artikelnummer: TGM-T16420-100mg
Description: P-1075 is a potent sulfonylurea receptor 2-associated ATP-sensitive potassium channels (SUR2-KIR6) activator (EC50 = 45 nM). P-1075 opens opens mitoKATP channels and may be cardioprotective. Target: Potassium Channel. Smiles: CCC(C)(C)N\C(NC#N)=N\c1cccnc1. References: Schwanstecher M, et al. Potassium...
| Anwendung: | Kir6 channel opener |
| CAS | 60559-98-0 |
| MW: | 231.3 D |
ab 54,00 €
P1075
Artikelnummer: Cay21849-1
P1075 is a potent activator of sulfonylurea receptor 2-associated ATP-sensitive potassium channels (SUR2-Kir6) with an EC50 value of 45 nM for SUR2B-Kir6 channel activation. It is highly selective for SUR2 over SUR1 isoforms (IC50s = 9-46 nM and 1.02 mM, respectively, in a radioligand binding assay). P1075 increases...
| Schlagworte: | N-cyano-N'-(1,1-dimethylpropyl)-N''-3-pyridinyl-guanidine |
| Anwendung: | Kir6 channel opener |
| CAS | 60559-98-0 |
| MW: | 231.3 D |
ab 66,00 €
