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NSC 146109 hydrochloride
NSC 146109 hydrochloride

Artikelnummer: TGM-T12257-10mg

Description: NSC 146109 hydrochloride is an activator of p53 targeting MDMX. NSC 146109 hydrochloride can be used for studies on breast cancer. Target: Others, Apoptosis. Smiles: Cl.Cc1c2ccccc2c(CSC(N)=N)c2ccccc12. References: Wang H, et al. A small-molecule p53 activator induces apoptosis through inhibiting MDMX...
Anwendung: p53 activator
CAS 59474-01-0
MW: 316.85 D
ab 34,00 €
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NSC 146109 (hydrochloride)
NSC 146109 (hydrochloride)

Artikelnummer: Cay16430-10

NSC 146109 is an activator of the tumor suppressor p53 that increases expression of p53 and the p53 target DR5 in wild-type and p53-knockout HCT116 colon adenocarcinoma cells. It is selective for p53, having no effect on p73 expression in HCT116 cells at a concentration of 2 µM. NSC 146109 activates p53, which...
Schlagworte: XI-011, carbamimidothioic acid, (10-methyl-9-anthracenyl)methyl ester, monohydrochloride
Anwendung: p53 activator
CAS 59474-01-0
MW: 316.8 D
ab 98,00 €
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