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PIK-93
PIK-93

Artikelnummer: TGM-T2616-100mg

Description: PIK-93, the first potent synthetic PI4K inhibitor, exhibits an IC50 of 19 nM and also inhibits PI3Kalpha with an IC50 of 39 nM. Target: PI3K, mTOR, ATM/ATR, PI4K, DNA-PK, HSV, Carbonic Anhydrase, Virus Protease. Smiles: CC(=O)Nc1nc(C)c(s1)-c1ccc(Cl)c(c1)S(=O)(=O)NCCO. References: Knight ZA, Cell,...
Schlagworte: PIK 93
Anwendung: PI4K-beta inhibitor
CAS 593960-11-3
MW: 389.88 D
ab 38,00 €
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PIK-93
PIK-93

Artikelnummer: Cay10009212-10

PIK-93 is an inhibitor of phosphatidylinositol 4-kinase IIIbeta (PI4KIIIbeta, IC50 = 19 nM). It is selective for PI4KIIIbeta over PI4KIIIalpha and PI4KIIalpha (IC50s = 1,100 and >100,000 nM, respectively). However, it also inhibits the PI3K catalytic subunits (IC50s = 39, 590, 120, and 16 nM for p110alpha, p110beta,...
Schlagworte: N-[5-[4-chloro-3-[[(2-hydroxyethyl)amino]sulfonyl]phenyl]-4-methyl-2-thiazolyl]-acetamide
Anwendung: PI4K-beta inhibitor
CAS 593960-11-3
MW: 389.9 D
ab 44,00 €
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PIK-93
PIK-93

Artikelnummer: LKT-P3542.1

PIK93 is an inhibitor of PI3K that exhibits some selectivity for p110 and p110 . PIK93 also inhibits PI4KIII , a phosphatidylinositol enzyme similar to PI3K. PIK93 decreases translocation of transient receptor potential canonical 6 channel (TRPC6) to the plasma membrane in vitro and may alter Ca2+ signaling as a...
Schlagworte: PIK93
Anwendung: PI4KB inhibitor
CAS 593960-11-3
MW: 389.88 D
ab 215,00 €
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PIK-93
PIK-93

Artikelnummer: SYN-1066-M001

Soluble in DMSO. Slightly soluble (<1mg/ml) in ethanol. PIK-93 selectively inhibits the type III PI 4-kinase beta enzyme (IC(50) of 19nM). It has also been shown to have activity on PI3Kalpha with an IC(50) of 39nM. Target: PI3K , Kinase Group: Lipid Kinase , Substrate: Lipid
Schlagworte: PIK93
Anwendung: PI4KB inhibitor
CAS 593960-11-3
MW: 389,9 D
ab 162,00 €
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