Zu "552325-16-3" wurden 3 Artikel gefunden!
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A-443654
Artikelnummer: TGM-T14072-100mg
Description: A-443654, a pan-Akt inhibitor, exhibits equal potency against Akt1, Akt2, and Akt3 within cells (Ki=160 pM). Target: MAPK, Casein Kinase, PKC, Src, Akt, FLT, Chk, GSK-3, CDK, ERK, VEGFR, PKA, S6 Kinase. Smiles: C([C@@H](COC=1C=C(C=NC1)C=2C=C3C(=CC2)NN=C3C)N)C=4C=5C(NC4)=CC=CC5. References:...
| Anwendung: | Potent and selective Akt inhibitor |
| CAS | 552325-16-3 |
| MW: | 397.47 D |
ab 82,00 €
A-443654
Artikelnummer: Cay16499-500
Three related forms of the kinase Akt (1, 2, 3, also known as protein kinase B isoforms PKBalpha, beta, gamma) modulate cell proliferation, metabolism, and survival as well as angiogenesis. A-443654 is an inhibitor of Akt (Ki = 160 pmol/L for all three isoforms) that interferes with mitotic progression and bipolar...
| Schlagworte: | alphaS-[[[5-(3-methyl-1H-indazol-5-yl)-3-pyridinyl]oxy]methyl]-1H-indole-3-ethanamine |
| Anwendung: | Akt inhibitor |
| CAS | 552325-16-3 |
| MW: | 397.5 D |
ab 92,00 €
A-443654
Artikelnummer: AG-CR1-3663-M001
White to off-white solid. Soluble in DMSO (15mg/ml), ethanol (10mg/ml) or DMF (20mg/ml). Potent and selective Akt inhibitor (Ki=160pmol/L for all three isoforms PKBalpha, PKBbeta and PKBgamma), DYRK1A inhibitor (IC50=10nM). Inhibits other kinases, including PRK2, MSK1 and DYRK3 at low nM range as well, Interferes...
| Schlagworte: | (S)-1-(1H-Indol-3-yl)-3-((5-(3-methyl-1H-indazol-5-yl)pyridin-3-yl)oxy)propan-2-amine |
| Anwendung: | Potent and selective Akt inhibitor |
| CAS | 552325-16-3 |
| MW: | 397,5 D |
ab 105,00 €
