Zu "541550-19-0" wurden 2 Artikel gefunden!
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Apilimod
Artikelnummer: TGM-T2018-100mg
Description: Apilimod (STA 5326) inhibits the production of IL-12 and IL-23 and reduces dendritic cell infiltration in psoriasis. Target: PI3K, Interleukin, IL Receptor. Smiles: Cc1cccc(\C=N\Nc2cc(nc(OCCc3ccccn3)n2)N2CCOCC2)c1. References: Wada Y, et al. PLoS One. 2012,7(4):e35069.
| Schlagworte: | STA 5326 |
| CAS | 541550-19-0 |
| MW: | 418.49 D |
ab 43,00 €
Apilimod
Artikelnummer: Cay19094-5
Apilimod is an inhibitor of the class III phosphatidylinositol kinase PIKfyve (IC50 = 14 nM). It is selective for PIKfyve over 10 other lipid kinases and 31 other protein kinases (IC50s = >9.1 µM for all). Apilimod inhibits the production of IL-12p40 induced by IFN-gamma and LPS or the TLR7 agonist R-837 (imiquimod,...
| Schlagworte: | STA-5326, 3-methyl-2-[6-(4-morpholinyl)-2-[2-(2-pyridinyl)ethoxy]-4-pyrimidinyl]hydrazone, benzaldehyde |
| Anwendung: | PIKfyve inhibitor, IL-12p40 production inhibitor |
| CAS | 541550-19-0 |
| MW: | 418.5 D |
ab 55,00 €
