Zu "54-36-4" wurden 2 Artikel gefunden!
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Metyrapone
Artikelnummer: TGM-T0293-100mg
Description: Metyrapone (NSC-25265) is an inhibitor of the enzyme STEROID 11-BETA-MONOOXYGEN ASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME. Target: Dehydrogenase, Autophagy, Others, P450. Smiles: CC(C)(C(=O)c1cccnc1)c1cccnc1. References: Shiro Y,...
| Schlagworte: | NSC-25265, Su-4885 |
| CAS | 54-36-4 |
| MW: | 226.27 D |
ab 34,00 €
Metyrapone
Artikelnummer: Cay14994-1
Metyrapone is an inhibitor of the cytochrome P450 (CYP) enzyme 11beta-hydroxylase (IC50 = 7.83 µM), an enzyme involved in the final step of cortisol biosynthesis. It also induces Cyp1a1 and Cyp3a4 expression in rat hepatic microsomes and inhibits the activity of 11beta-hydroxysteroid dehydrogenase type 1...
| Schlagworte: | NSC 25265, SU 4885, 2-methyl-1,2-di-3-pyridinyl-1-propanone |
| Anwendung: | 11beta-hydroxylase inhibitor, CYP450 inhibitor |
| CAS | 54-36-4 |
| MW: | 226.3 D |
ab 34,00 €
