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UF010
Artikelnummer: TGM-T3205-100mg
Description: UF010 is a potent and selective HADC inhibitor with IC50 ~0.06 µM, 0.1 µM, 0.5 µM and 1.5 µM for HDACs 3, 2, 1 and 8, respectively. Target: HDAC. Smiles: CCCCNNC(=O)c1ccc(Br)cc1. References: Wang Y, et al. Identification of histone deacetylase inhibitors with benzoylhydrazide scaffold that selectively...
| Anwendung: | Class I HDAC inhibitor |
| CAS | 537672-41-6 |
| MW: | 271.15 D |
ab 31,00 €
UF010
Artikelnummer: Cay21273-25
UF010 is a class I HDAC inhibitor with IC50 values of 0.06, 0.1, 0.5, and 1.5 µM for HDAC3, 2, 1, and 8, respectively. It is more than 6-fold selective for these class I HDACs over any additional HDACs. UF010 is reported to inhibit cancer cell proliferation with a mean GI50 value of 2.94 µM when screened against the...
| Schlagworte: | 4-bromo-benzoic acid, 2-butylhydrazide |
| Anwendung: | Class I HDAC inhibitor |
| CAS | 537672-41-6 |
| MW: | 271.2 D |
ab 61,00 €
