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QX-314 chloride
Artikelnummer: TGM-T12608-100mg
Description: QX-314 chloride is a membrane-impermeable, permanently charged blocker of the sodium channel. Target: Sodium Channel. Smiles: [Cl-].CC[N+](CC)(CC)CC(=O)Nc1c(C)cccc1C. References: Rivera-Acevedo RE, et al. The quaternary lidocaine derivative, QX-314, exerts biphasic effects on transient receptor...
| Anwendung: | Sodium channel blocker |
| CAS | 5369-03-9 |
| MW: | 298.85 D |
ab 48,00 €
QX-314 (chloride)
Artikelnummer: Cay18454-50
QX-314 is a membrane-impermeant lidocaine derivative that selectively blocks sodium channels on nociceptive neurons when delivered intracellularly via the TRPV1 channel, but is reportedly ineffective with extracellular application. When supplied in combination with 1 µM capsaicin (Cay-92350), a TRPV1 receptor...
| Schlagworte: | N-Ethyllidocaine, 2-[(2,6-dimethylphenyl)amino]-N,N,N-triethyl-2-oxo-ethanaminium, monochloride |
| Anwendung: | Sodium channel blocker |
| CAS | 5369-03-9 |
| MW: | 298.9 D |
163,00 €
