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PF-4878691
Artikelnummer: TGM-T16506-100mg
Description: PF-4878691 (3M-852A) is a potent and selective Toll-like receptor 7 agonist, designed to dissociate its antiviral and inflammatory activities. Target: TLR. Smiles: CCc1nc2c(N)nc3ccccc3c2n1CCCCNS(C)(=O)=O. References: Fidock MD, et al. The innate immune response, clinical outcomes, and ex vivo HCV...
| Schlagworte: | 3M-852A |
| Anwendung: | TLR7 agonist |
| CAS | 532959-63-0 |
| MW: | 361.46 D |
ab 40,00 €
852A
Artikelnummer: Cay39512-1
852A is a toll-like receptor 7 (TLR7) agonist. It selectively induces NF-kappaB signaling in HEK293 cells expressing recombinant human TLR7 but not HEK293 cells expressing recombinant human TLR8 or TLR9 when used at a concentration of 1 µM. 852A (10-1,000 ng/ml) also induces IFN-alpha production in plasmacytoid...
| Schlagworte: | PF-4878691, N-[4-(4-amino-2-ethyl-1H-imidazo[4,5-c]quinolin-1-yl)butyl]-methanesulfonamide |
| Anwendung: | TLR7 agonist |
| CAS | 532959-63-0 |
| MW: | 361.5 D |
ab 54,00 €
