Zu "53123-88-9" wurden 4 Artikel gefunden!
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Rapamycin
Artikelnummer: Cay13346-1
Rapamycin is an allosteric inhibitor of the mammalian target of rapamycin (mTOR) complex 1 (mTORC1) originally isolated from S. hygroscopicus. It interacts with FKBP prolyl isomerase 1A (FKBP12) to form a complex that binds to and inhibits the kinase activity of mTORC1. Rapamycin inhibits growth of Rh1 and Rh30...
| Schlagworte: | AY 22989, NSC 226080, Wy 090217,... |
| Anwendung: | mTORC1 blocking |
| CAS | 53123-88-9 |
| MW: | 914.2 D |
ab 50,00 €
Rapamycin
Artikelnummer: AG-CN2-0025-M001
Isolated from Streptomyces hygroscopicus. Antibiotic. Antibacterial and antifungal properties. Forms a complex with FKBP12 and inhibits the molecular target of rapamycin (mTOR). Inhibits the response to interleukin-2 (IL-2), and thereby blocks activation of T and B cells. Potent immunosuppressant used as an...
| Schlagworte: | Sirolimus, Rapamune, NSC 226080, Antibiotic AY-22989, WY-090217, RAPA, SILA 9268A, CCRIS 9024 |
| Anwendung: | mTOR inhibitor, Immunsuppressant, Apoptosis inducer |
| CAS | 53123-88-9 |
| MW: | 914,2 D |
ab 28,00 €
Rapamycin
Artikelnummer: LKT-R0161.10
Macrolide originally produced by Streptomyces, mTOR inhibitor.
| Schlagworte: | Sirolimus, Rapamune, AY-22989 |
| Anwendung: | Antibiotic |
| CAS | 53123-88-9 |
| MW: | 914,17 D |
ab 64,00 €
Rapamycin (FRAP, mTOR Inhibitor)
Artikelnummer: R1137-01.10
Rapamycin is a bacterial macrolide with antifungal and immunosuppressant activities , (1). Rapamycin forms a complex with the immunophilin FKBP12 which then inhibits the activity of FRAP/mTOR (TOR in yeast) (2,3). Rapamycin treatment of cells leads to the dephosphorylation and inactivation of p70 S6 kinase....
| CAS | 53123-88-9 |
| MW: | 914.20 D |
ab 265,00 €
