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Sulfaphenazole
Sulfaphenazole

Artikelnummer: TGM-T4567-100mg

Description: Sulfaphenazole (Plisulfan) is an inhibitor of CYP2C9 (Ki: 0.3 µM) that demonstrates at least 100-fold selectivity over other CYP450 isoforms (Ki: 63/29 µM for CYP2C8/CYP2C18, respectively, and no activity at CYP1A1, CYP1A2, CYP3A4, CYP2C19). At 10 µM, sulfaphenazole has been shown to inhibit...
Schlagworte: Raziosulfa, Depocid, Depotsulfonamide, Plisulfan
Anwendung: Targets dihydropteroate synthase [EC:2.5.1.15] (folP)
CAS 526-08-9
MW: 314.36 D
ab 48,00 €
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Sulfaphenazole
Sulfaphenazole

Artikelnummer: Cay14844-250

CYP2C9 is a major cytochrome P450 enzyme that is involved in the metabolic clearance of various therapeutic agents. Disruption of this enzyme's activity can lead to adverse drug reactions. Sulfaphenazole is an inhibitor of CYP2C9 (Ki = 0.3 µM) that demonstrates at least 100-fold selectivity over other CYP450...
Schlagworte: Depocid, Depotsulfonamide, Plisulfan, Raziosulfa, 4-amino-N-(1-phenyl-1H-pyrazol-5-yl)-benzenesulfonamide
Anwendung: CYP2C9 inhibitor
CAS 526-08-9
MW: 314.4 D
ab 161,00 €
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