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PMX-53 TFA
PMX-53 TFA

Artikelnummer: TGM-T83669-10mg

Description: PMX-53, a macrocyclic complement 5a (C5a) peptidomimetic and C5a receptor antagonist (IC50 = 0.3 µM), effectively inhibits the C5a-induced secretion of myeloperoxidase (MPO) in isolated human polymorphonuclear leukocytes (PMNs). Administered orally at 10 mg/kg, PMX-53 mitigates vascular leakage, PMN...
Schlagworte: AcPhe-[Orn-Pro-D-Cyclohexylalanine-Trp-Arg], 3D53, AcF-[OPdChaWR]
Anwendung: C5a receptor antagonist
CAS 514814-99-4
MW: 896.09 D
ab 148,00 €
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PMX-53 (trifluoroacetate salt)
PMX-53 (trifluoroacetate salt)

Artikelnummer: Cay35840-10

PMX-53 is a macrocyclic complement 5a (C5a) peptidomimetic and an antagonist of the C5a receptor (IC50 = 0.3 µM). It inhibits C5a-induced secretion of myeloperoxidase (MPO) in isolated human polymorphonuclear leukocytes (PMNs). PMX-53 (10 mg/kg, p.o.) inhibits vascular leakage, PMN infiltration, and peritoneal...
Schlagworte: 3D53, AcF-[OPdChaWR], AcPhe-[Orn-Pro-D-Cyclohexylalanine-Trp-Arg], (6->2)-lactam,...
Anwendung: C5a receptor antagonist
CAS 514814-99-4
MW: 896.1 D
ab 82,00 €
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