Zu "509093-47-4" wurden 2 Artikel gefunden!
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IRAK-1/4 Inhibitor
Artikelnummer: Cay17540-1
Interleukin-1 receptor-associated kinases (IRAKs) are important mediators in the signal transduction of Toll/IL-1 receptor (TIR) family members. Dysregulation of TIR signaling, typified by increased NF-kappaB activity, results in the development of some cancers and other diseases, making the development of IRAK...
| Schlagworte: | N-[1-[2-(4-morpholinyl)ethyl]-1H-benzimidazol-2-yl]-3-nitro-benzamide |
| Anwendung: | IRAK1 inhibitor, IRAK4 inhibitor |
| CAS | 509093-47-4 |
| MW: | 395.4 D |
ab 44,00 €
IRAK-1-4 Inhibitor I
Artikelnummer: TGM-T2457-100mg
Description: IRAK-1-4 Inhibitor I is a dual inhibitor targeting IRAK1 and IRAK4. Target: IRAK. Smiles: [O-][N+](=O)c1cccc(c1)C(=O)Nc1nc2ccccc2n1CCN1CCOCC1. References: Powers JP, et al. Discovery and initial SAR of inhibitors of interleukin-1 receptor-associated kinase-4. Bioorg Med Chem Lett. 2006 Jun...
| Schlagworte: | IRAK-1/4 Inhibitor I, IRAK-1/4 Inhibitor |
| Anwendung: | IRAK-1-4 inhibitor |
| CAS | 509093-47-4 |
| MW: | 395.41 D |
ab 38,00 €
