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Odevixibat
Odevixibat

Artikelnummer: TGM-T16376-100mg

Description: Odevixibat (A4250) is an effective, selective and orally active ileal bile acid transporter inhibitor. Odevixibat has the potential for the treatment of primary biliary cirrhosis. Odevixibat reduces cholestatic liver and bile duct injury in mice model. Target: Others. Smiles:...
Schlagworte: A4250
Anwendung: Targets solute carrier family 10 (sodium/bile acid cotransporter), member 2 (SLC10A2, ASBT)
CAS 501692-44-0
MW: 740.93 D
ab 54,00 €
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Odevixibat
Odevixibat

Artikelnummer: Cay35344-1

Odevixibat is an inhibitor of the sodium/bile acid and sulfated solute cotransporter (ASBT, IC50 = 0.16 nM). It inhibits intestinal reabsorption of [75Se]homotaurocholic acid (75SeHCAT) by 74% in ApoE-/- mice when administered at a dose of 0.156 µmol/kg. Formulations containing odevixibat have been used in the...
Schlagworte: A4250,...
Anwendung: ASBT (sodium/bile acid cotransporter) inhibitor
CAS 501692-44-0
MW: 740.9 D
ab 44,00 €
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