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AR-C155858
AR-C155858

Artikelnummer: TGM-T14316-100mg

Description: AR-C155858 is an inhibitor of monocarboxylate transporter MCT1 and MCT2 (Kis: 2.3 nM and 10 nM). Target: Monocarboxylate transporter. Smiles: CC(C)Cn1c2sc(Cc3c(C)n[nH]c3C)c(C(=O)N3C[C@H](O)CO3)c2c(=O)n(C)c1=O. References: Ovens MJ, et al. The inhibition of monocarboxylate transporter 2 (MCT2) by...
Anwendung: Monocarboxylate transporter 1/2 inhibitor
CAS 496791-37-8
MW: 461.53 D
ab 95,00 €
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AR-C 155858
AR-C 155858

Artikelnummer: Cay14884-1

AR-C 155858 is an inhibitor of monocarboxylate transporter 1 (MCT1) and MCT2 (Kis = 2.3 and Xenopus oocytes expressing the human receptors). It is selective for MCT1 and MCT2 over MCT4 (Ki = >10 µM). AR-C 155858 inhibits L-lactate uptake in and proliferation of murine 4T1 breast cancer cells (IC50s = 25 and 20.2 nM,...
Schlagworte: 6-[(3,5-dimethyl-1H-pyrazol-4-yl)methyl]-5-[[(4S)-4-hydroxy-2-isoxazolidinyl]carbonyl]-3-methyl-1-(2-methylpropyl)-thieno[...
Anwendung: Monocarboxylate transporter 1/2 inhibitor
CAS 496791-37-8
MW: 461.5 D
331,00 €
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