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Radiprodil
Artikelnummer: TGM-T5385-100mg
Description: Radiprodil (RGH-896) (RGH-896) is an orally active and selective NMDA NR2B receptors antagonist. It was a potential treatment of neuropathic pain associated with diabetic peripheral neuropathy (DPNP). Target: NMDAR, iGluR. Smiles: Fc1ccc(CC2CCN(CC2)C(=O)C(=O)Nc2ccc3[nH]c(=O)oc3c2)cc1. References: Labas...
| Schlagworte: | RGH-896 |
| Anwendung: | NR2B subunit-containing NMDA receptor antagonist |
| CAS | 496054-87-6 |
| MW: | 397.4 D |
ab 42,00 €
Radiprodil
Artikelnummer: Cay29712-10
Radiprodil is an antagonist of NR2B subunit-containing NMDA receptors (IC50 = 8 nM). It is selective for NR2B subunit-containing NMDA receptors over NR1 and NR2A subunit-containing NMDA receptors at 15 µM. Radiprodil (10 nM) reduces amyloid beta (1-42) (Abeta42) and Abeta40-induced decreases in dendritic spine...
| Schlagworte: | N-(2,3-dihydro-2-oxo-6-benzoxazolyl)-4-[(4-fluorophenyl)methyl]-alpha-oxo-1-piperidineacetamide |
| Anwendung: | NR2B subunit-containing NMDA receptor antagonist |
| CAS | 496054-87-6 |
| MW: | 397.4 D |
ab 149,00 €
