Zu "495399-09-2" wurden 2 Artikel gefunden!
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Saroglitazar
Artikelnummer: TGM-T12835-10mg
Description: Saroglitazar (Lipaglyn) is an agonist of PPAR with EC50 values of 0.65 pM and 3 nM for PPARalpha and PPARgamma. Target: PPAR. Smiles: CCO[C@@H](Cc1ccc(OCCn2c(C)ccc2-c2ccc(SC)cc2)cc1)C(O)=O. References: Jain MR, et al. Saroglitazar, a novel PPARalpha/gamma agonist with predominant PPARalpha activity,...
| Schlagworte: | Lipaglyn |
| Anwendung: | PPARalpha agonist, PPARgamma agonist |
| CAS | 495399-09-2 |
| MW: | 439.57 D |
ab 149,00 €
Saroglitazar
Artikelnummer: Cay27851-2.5
Saroglitazar is a dual agonist of PPARalpha and PPARgamma (EC50s = 0.65 and 3,000 pM, respectively, in a transactivation assay in HepG2 cells). It decreases serum triglyceride, free fatty acid, and glucose levels in a db/db mouse model of diabetes when administered at doses ranging from 0.01 to 3 mg/kg per day for...
| Schlagworte: | alphaS-ethoxy-4-[2-[2-methyl-5-[4-(methylthio)phenyl]-1H-pyrrol-1-yl]ethoxy]-benzenepropanoic acid |
| Anwendung: | PPARalpha agonist, PPARgamma agonist |
| CAS | 495399-09-2 |
| MW: | 439.6 D |
530,00 €
