Zu "477600-75-2" wurden 2 Artikel gefunden!
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Tofacitinib
Artikelnummer: TGM-T6321-100mg
Description: Tofacitinib (Tasocitinib) is a Janus kinase inhibitor that inhibits JAK3/2/1 (IC50=1/20/112 nM) and is orally active. Tofacitinib is used for the treatment of moderate to severe rheumatoid arthritis. Target: JAK, Apoptosis, ROCK, Src. Smiles: C[C@@H]1CCN(C[C@@H]1N(C)C1=C2C=CNC2=NC=N1)C(=O)CC#N....
| Schlagworte: | CP-690550, Tasocitinib |
| Anwendung: | Targets Janus kinase 1 [EC:2.7.10.2] (JAK1) |
| CAS | 477600-75-2 |
| MW: | 312.37 D |
ab 31,00 €
COVID-19 Forschung
Tofacitinib
Artikelnummer: AG-CR1-3625-M005
Off-white to pale yellow solid. Soluble in DMSO or ethanol. Potent cell permeable JAK3 inhibitor (IC50 = 1nM). Shows also JAK-1 inhibitory activity, Immunosuppressive and anti-inflammatory agent, Inhibits signaling through heterodimeric receptors associated with JAK3, JAK1, or both of them, with functional...
| Schlagworte: | CP-690550, Xeljanz, Tasocitinib |
| Anwendung: | Cell-permeable JAK3 inhibitor |
| CAS | 477600-75-2 |
| MW: | 312,4 D |
ab 77,00 €
