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Sorafenib tosylate
Artikelnummer: TGM-T0093-50mg
Description: Sorafenib tosylate (Bay 43-9006) is a potent multikinase inhibitor (IC50s: 6/20/22 nM for Raf-1/VEGFR-3/B-Raf). Target: VEGFR, c-Kit, PDGFR, Autophagy, FLT, Apoptosis, Raf, Ferroptosis. Smiles: Cc1ccc(cc1)S(O)(=O)=O.CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)cc2)ccn1. References: Wei JC, et...
| Schlagworte: | Bay 43-9006 |
| CAS | 475207-59-1 |
| MW: | 637.03 D |
ab 38,00 €
![Sorafenib, p-Toluenesulfonate Salt (4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy](https://www.biomol.com/media/image/de/eb/be/S5343-15-5_200x200.jpg "Sorafenib, p-Toluenesulfonate Salt (4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy")
Sorafenib, p-Toluenesulfonate Salt...
Artikelnummer: S5343-15.1
Sorafenib (Bay 43-9006) is a novel bi-aryl urea compound that inhibits cell proliferation by targeting the ERK pathway and angiogenesis by targeting the receptor tyrosine kinases VEGFR-2 and PDGFR-b and their associated signaling cascades. Although sorafenib was initially developed as a Raf kinase inhibitor...
| Anwendung: | Tyrosine protein kinase inhibitor |
| CAS | 475207-59-1 |
| MW: | 637.03 |
ab 269,00 €
Sorafenib (tosylate)
Artikelnummer: Cay35612-10
Sorafenib is a multi-kinase inhibitor that inhibits Raf-1 and B-RAF (IC50s = 6 and 22 µM, respectively), as well as the receptor tyrosine kinases VEGFR2, VEGFR3, PDGFRbeta, FLT3, and c-Kit (IC50s = 90, 15, 20, 57, and 58 nM, respectively). It is selective for these kinases over 12 other kinases, including ERK1,...
| Schlagworte: | BAY 43-9006 mono-p-tosylate, BAY 54-9085,... |
| Anwendung: | Multi-kinase inhibitor |
| CAS | 475207-59-1 |
| MW: | 637 D |
ab 87,00 €
