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Monomethyl auristatin E
Artikelnummer: TGM-T6897-10mg
Description: Monomethyl auristatin E (MMAE) (MMAE), an antimitotic agent, inhibits cell division by blocking the polymerization of tubulin and also has inhibition of antibody-drug conjugates (ADCs) activity. Target: Microtubule Associated, Apoptosis, ADC Cytotoxin. Smiles:...
| Schlagworte: | Vedotin, MMAE |
| Anwendung: | Targets tubulin beta (TUBB) |
| CAS | 474645-27-7 |
| MW: | 717.98 D |
ab 42,00 €
Monomethyl Auristatin E
Artikelnummer: Cay16267-5
Dolastatin 10 is a natural antimitotic and antineoplastic agent that binds to tubulin and inhibits tubulin polymerization. Monomethyl Auristatin E (MMAE) is a synthetic analog of dolastatin 10 that similarly inhibits tubulin polymerization and exhibits potent cytotoxicity. It is commonly conjugated with monoclonal...
| Schlagworte: | Brentuximab vedotin, MMAE,... |
| Anwendung: | Antineoplastic agent, Antimitotic |
| CAS | 474645-27-7 |
| MW: | 718 D |
ab 111,00 €
