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AKT-I-1
Artikelnummer: TGM-T25017-100mg
Description: AKT-I-1 is a selective and reversible inhibitor of Akt1. Target: Akt. Smiles: CN(C)CC(C)(C)CNc1nn2c(nnc2cc1C1CCC1)-c1ccccc1. References: Zhang Q, et al. Autophagy prevention sensitizes AKTi-1/2-induced anti-hepatocellular carcinoma cell activity in vitro and in vivo. Biochem Biophys Res Commun. 2016 Nov...
| Anwendung: | Akt1 inhibitor |
| CAS | 473382-39-7 |
| MW: | 378.51 D |
ab 228,00 €
Akt-I-1
Artikelnummer: Cay41016-1
Akt-I-1 is an inhibitor of Akt1 (IC50 = 4.6 µM). It is selective for Akt1 over Akt2, Akt3, and serum/glucocorticoid-regulated kinase (SGK, IC50s = >250 µM for all).Formal Name: N3-(7-cyclobutyl-3-phenyl-1,2,4-triazolo[4,3-b]pyridazin-6-yl)-N1,N1,2,2-tetramethyl-1,3-propanediamine. CAS Number: 473382-39-7. Synonyms:...
| Schlagworte: | Akt-IN-1, N3-(7-cyclobutyl-3-phenyl-1,2,4-triazolo[4,3-b]pyridazin-6-yl)-N1,N1,2,2-tetramethyl-1,3-propanediamine |
| Anwendung: | Akt1 inhibitor |
| CAS | 473382-39-7 |
| MW: | 378.5 D |
ab 195,00 €
Akt-I-1
Artikelnummer: SYN-1005-M001
Soluble in DMSO. The compound (Akt-I-1) inhibits only Akt1 (IC(50) 4.6 µM) and does not inhibit AKT2, or AKT3. The compound is a reversible inhibitor, and exhibits a linear mixed-type inhibition against ATP and peptide substrate. In addition to inhibiting kinase activity of AKT1 isoform, AKT-I-1 blocked the...
| Schlagworte: | AktI1 |
| Anwendung: | Akt1 inhibitor |
| CAS | 473382-39-7 |
| MW: | 378,5 D |
ab 256,00 €
