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Ko 143
Artikelnummer: TGM-TQ0186-10mg
Description: Ko 143 is a selective inhibitor of ATP-binding cassette sub-family G member 2 (ABCG2, BCRP). Target: BCRP, ABC. Smiles: COc1ccc2c3C[C@@H]4N([C@@H](CC(C)C)c3[nH]c2c1)C(=O)[C@H](CCC(=O)OC(C)(C)C)NC4=O. References: Weidner LD, et al. The Inhibitor Ko143 Is Not Specific for ABCG2. J Pharmacol Exp Ther....
| Anwendung: | ABCG2 inhibitor |
| CAS | 461054-93-3 |
| MW: | 469.57 D |
ab 39,00 €
Ko 143
Artikelnummer: Cay15215-5
Breast cancer resistance protein (BCRP) is an ATP-binding cassette protein known also as ABCG2. While it normally functions as a high-capacity urate exporter in the renal system, it also acts as a xenobiotic transporter and contributes to multidrug resistance (e.g., to mitoxantrone) in certain types of cancer. BCRP...
| Schlagworte: | (3S,6S,12aS)-1,2,3,4,6,7,12,12a-octahydro-9-methoxy-6-(2-methylpropyl)-1,4-dioxo-pyrazino[1',2':1,6]pyrido[3,4-b]indole-3-... |
| Anwendung: | ABCG2 inhibitor |
| CAS | 461054-93-3 |
| MW: | 469.6 D |
ab 161,00 €
