Zu "459789-99-2" wurden 2 Artikel gefunden!
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6-ECDCA
Artikelnummer: AG-CR1-3560-M005
Potent and selective farnesoid X receptor FXR agonist (EC50= 99nM) [1]. Induces SHP in HSCs to suppress TIMP-1 expression [2]. Apoptosis inducer [2]. Protects against liver fibrosis development in rat in vivo [2]. Displays anticholeretic activity in rat in vivo [3]. Promotes preadipocyte differentiation [4]....
| Schlagworte: | 6alpha-Ethyl-chenodeoxycholic acid, 6-alpha-ECDC, Obeticholic acid, INT-747, OCA |
| Anwendung: | FXR agonist |
| CAS | 459789-99-2 |
| MW: | 420,3 D |
ab 66,00 €
6-ECDCA
Artikelnummer: Cay11031-5
Farnesoid X receptor (FXR) is a nuclear receptor that is activated by bile acid, with chenodeoxycholic acid (CDCA) being a representative natural ligand. 6-ECDCA is a synthetic bile acid that acts as a potent and selective agonist of FXR (EC50 = 99 nM). Through FXR, it alters gene expression that results in...
| Schlagworte: | INT 747, Obeticholic Acid, (3alpha,5beta,6alpha,7alpha)-6-ethyl-3,7-dihydroxy-cholan-24-oic acid |
| Anwendung: | FXR agonist |
| CAS | 459789-99-2 |
| MW: | 420.6 D |
ab 135,00 €
