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SW033291
Artikelnummer: TGM-T2121-100mg
Description: SW033291 is a small-molecule inhibitor of 15-PGDH (Ki=0.1 nM) that increases prostaglandin PGE2 levels in bone marrow and other tissues. Target: Dehydrogenase. Smiles: CCCCS(=O)c1sc2nc(cc(-c3ccccc3)c2c1N)-c1cccs1. References: Zhang Y, et al. Science. 2015, 348(6240), aaa2340.
| CAS | 459147-39-8 |
| MW: | 412.59 D |
ab 34,00 €
SW033291
Artikelnummer: Cay18040-5
The enzyme 15-hydroxy prostaglandin dehydrogenase (15-PGDH) initiates the catabolism of PGs and related eicosanoids. SW033291 is a potent inhibitor of 15-PGDH (Ki = ~0.1 nM) that has activity in vivo. It rapidly increases the levels of PGE2 in bone marrow and other tissues in mice after intraperitoneal injection....
| Schlagworte: | 2-(butylsulfinyl)-4-phenyl-6-(2-thienyl)-thieno[2,3-b]pyridine-3-amine |
| Anwendung: | 15-PGDH inhibitor |
| CAS | 459147-39-8 |
| MW: | 412.6 D |
ab 62,00 €
