Zu "457081-03-7" wurden 2 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
JAK Inhibitor I
Artikelnummer: Cay15146-1
Janus-associated kinases (JAKs) are cytoplasmic tyrosine kinases that are required for activating the signaling of certain cytokines and growth factor receptors. JAK1 mostly activates IL-6, whereas JAK1 and JAK3 trigger IL-2 and IL-4 and JAK1 and JAK2 stimulates IFN-gamma. JAK Inhibitor I is a pyridine-containing...
| Schlagworte: | CMP 6, Janus-Associated Kinase Inhibitor I, Pyridone 6,... |
| Anwendung: | JAK2, JAK3, JAK1 inhibitor |
| CAS | 457081-03-7 |
| MW: | 309.3 D |
ab 39,00 €
Merck-5
Artikelnummer: SYN-1054-M001
Soluble in DMSO. Merck 5, also known as Pyridone 6, is a potent and reversible ATP-competitive inhibitor of the JAK kinases (JAK1, JAK2, JAK3, and Tyk2) with IC(50) values in the low anomolar range. At higher values (IC(50) >100nM) Merck 5 also can inhibit ERK kinase family and appear to block IL-2 and IL-4...
| Schlagworte: | Pyridone 6 |
| Anwendung: | JAK / Tyk2 inhibitor |
| CAS | 457081-03-7 |
| MW: | 309,3 D |
ab 300,00 €
