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ABT-100
Artikelnummer: Cay41355-1
ABT-100 is an inhibitor of farnesyltransferase (FTase). It inhibits Ras farnesylation but not Rap1A geranylgeranylation in HepG2 and Huh7 cells when used at a concentration of 20 µM. ABT-100 (2-20 µM) inhibits the proliferation of the same cells. In vivo, ABT-100 (39 mg/kg per day) increases body weight and percent...
| Schlagworte: | A-367074,... |
| Anwendung: | FTase inhibitor |
| CAS | 450839-40-4 |
| MW: | 504.5 D |
ab 61,00 €
ABT-100
Artikelnummer: TGM-T10223-100mg
Description: ABT-100 is a potent, highly selective, and orally active inhibitor of farnesyl transferase [farnesyl-protein transferase] with broad-spectrum antitumor activity. Target: Others. Smiles: Cn1cncc1[C@](O)(COc1ccc(cc1-c1ccc(OC(F)(F)F)cc1)C#N)c1ccc(cc1)C#N. References: Ferguson D, et al. Antitumor activity...
| CAS | 450839-40-4 |
| MW: | 504.46 D |
ab 958,00 €
