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Pazopanib
Artikelnummer: Cay12097-10
Pazopanib is a multi-kinase inhibitor that inhibits the VEGF receptors VEGFR1, VEGFR2, and VEGFR3 (IC50s = 10, 30, and 47 nM, respectively, in a cell-free enzyme assay). It also inhibits PDGFRalpha, PDGFRbeta, and c-Kit (IC50s = 71, 84, and 74 nM, respectively, in a cell-free enzyme assay) as well as additional...
| Schlagworte: | GSK-VEG10003, GW786034B, 5-[[4-[(2,3-dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methyl-benzenesulfonamide |
| Anwendung: | Broad spectrum tyrosine kinase inhibitor |
| CAS | 444731-52-6 |
| MW: | 437.5 D |
ab 37,00 €
![Pazopanib, Free Base (5-[[4-[(2,3-Dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methy](https://www.biomol.com/media/image/95/7c/bf/P3113-97A-25_200x200.jpg "Pazopanib, Free Base (5-[[4-[(2,3-Dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methy")
Pazopanib, Free Base...
Artikelnummer: P3113-97A.25
Pazopanib is an oral, second-generation, potent and selective multi-targeted tyrosine kinase inhibitor that targets vascular endothelial growth factor receptor (VEGFR), platelet-derived growth factor receptor and c-kit, key proteins responsible for tumor growth and angiogenesis. Pazopanib showed good potency...
| CAS | 444731-52-6 |
| MW: | 437.52 |
249,00 €
Pazopanib (free base)
Artikelnummer: AG-CR1-3746-M250
White to off-white solid. Soluble in DMSO (10mg/ml). Insoluble in water. Chemical. CAS: 444731-52-6. Formula: C21H23N7O2S. MW: 437.5. Pazopanib is a potent and selective multi-targeted receptor tyrosine kinase inhibitor. It is an orally available angiogenesis inhibitor targeting vascular endothelial growth factor...
| Schlagworte: | GW-786034, GSK-VEG10003, Votrient, Armala |
| CAS | 444731-52-6 |
| MW: | 437,5 D |
ab 28,00 €
