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CK-666
CK-666

Artikelnummer: TGM-T10826-100mg

Description: CK-666 is a cell-permeable inhibitor of the actin-related protein Arp2/3 complex, binding to and stabilizing its inactive state, thereby preventing the movement of the Arp2 and Arp3 subunits into the activated filament-like (short pitch) configuration. Target: Microtubule Associated, HIV Protease....
CAS 442633-00-3
MW: 296.34 D
ab 34,00 €
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CK-666
CK-666

Artikelnummer: Cay29038-1

CK-666 is an inhibitor of the actin-related protein 2/3 (Arp2/3) complex (IC50s = 4, 17, and 5 µM for the human, bovine, and S. pombe complexes, respectively, in an actin polymerization assay). It binds at the Arp2/3 interface, stabilizing the inactive conformation of the complex. CK-666 (40 µM) inhibits actin comet...
Schlagworte: 2-fluoro-N-[2-(2-methyl-1H-indol-3-yl)ethyl]-benzamide
Anwendung: Arp2/3 complex inhibitor
CAS 442633-00-3
MW: 296.3 D
ab 43,00 €
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