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Salinosporamide A
Artikelnummer: AG-CN2-0444-C100
Potent, irreversible inhibitor of all the 3 proteolytic activities of the mammalian 20S proteasome. beta5 subunit: chymotrypsin-like (EC50 = 3.5nM) beta2 subunit: trypsin-like (EC50 = 28nM) beta1 subunit: caspase-like or peptidyl-glutamyl peptide-hydrolyzing (PGPH) (EC50 = 430nM) Potent anticancer compound. Triggers...
| Schlagworte: | SalA, Marizomib, NPI-0052 |
| Anwendung: | Potent irreversible mammalian 20S proteasome subunit beta1/2/5 inhibitor |
| CAS | 437742-34-2 |
| MW: | 313,8 D |
ab 143,00 €
Salinosporamide A
Artikelnummer: Cay10007311-100
Salinosporamide A is a natural proteasome inhibitor. It is a beta-lactone-gamma-lactam that irreversibly inhibits all three protease activities within the proteasome (IC50s = 3.5, 28, and 430 nM for beta5 (chymotrypsin), beta2 (macropain), and beta1 (C5) subunits, respectively), both in vitro and in vivo....
| Schlagworte: | Marizomib, ML-858, NPI-0052,... |
| Anwendung: | Natural proteasome inhibitor, PSMB5 / PSMB2 / PSMB1 inhibitor |
| CAS | 437742-34-2 |
| MW: | 313.8 D |
222,00 €
