Zu "436133-68-5" wurden 3 Artikel gefunden!
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Kobe0065
Artikelnummer: TGM-T1876-100mg
Description: Kobe0065 is a novel and effective small-molecule compound that inhibits the Ras-Raf interaction by structure-based drug design (SBDD), it displays potent activity, competitively inhibiting the binding of H-Ras·GTP to c-Raf-1 RBD with a Ki value of 46 ± 13 µM. Target: Raf, Apoptosis, Ras. Smiles:...
| Anwendung: | Ras inhibitor |
| CAS | 436133-68-5 |
| MW: | 449.79 D |
ab 39,00 €
Kobe 0065
Artikelnummer: Cay16261-5
The Ras family of small GTPases (H-Ras, K-Ras, and N-Ras) function as molecular switches, cycling between a GTP-bound active state and a GDP-bound inactive state, to turn on downstream Raf protein kinases. This initiates complex signaling pathways involved in cell growth, differentiation, and apoptosis. Mutations...
| Schlagworte: | N-(3-chloro-4-methylphenyl)-2-[2,6-dinitro-4-(trifluoromethyl)phenyl]-hydrazinecarbothioamide |
| Anwendung: | Ras inhibitor |
| CAS | 436133-68-5 |
| MW: | 449.8 D |
ab 50,00 €
Kobe 0065
Artikelnummer: LKT-K5604.25
Ras inhibitor.
| Anwendung: | Ras inhibitor |
| CAS | 436133-68-5 |
| MW: | 449.79 D |
ab 167,00 €
