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Teglarinad chloride
Artikelnummer: TGM-T26254-1mg
Description: Teglarinad chloride (GMX-1777 chloride) is a potent inhibitor of NAMPT, the precursor of GMX1778.Teglarinad chloride has antitumor activity and acts by interfering with DNA repair and inhibiting angiogenesis. Target: NAMPT. Smiles: [Cl-].COCCOCCOCC...
| Schlagworte: | GMX 1777, GMX-1777 chloride, GMX1777 chloride, GMX 1777 chloride, EB1627, GMX1777, EB-1627, EB-1627 chloride, EB1627 chloride |
| Anwendung: | Targets nicotinamide phosphoribosyltransferase [EC:2.4.2.12] (NAMPT) |
| CAS | 432037-57-5 |
| MW: | 672.6 D |
205,00 €
GMX1777
Artikelnummer: Cay38798-1
GMX1777 is a prodrug form of the nicotinamide phosphoribosyltransferase (Nampt) inhibitor CHS-828 (Cay-11021). Intravenous administration of GMX1777 (75 and 150 mg/kg) reduces NAD+ levels in tumors, but not muscle tissue, in a DMS 273 lung cancer mouse xenograft model. GMX1777 (50 mg/kg per day), in combination with...
| Schlagworte: | EB1627, Teglarinad,... |
| Anwendung: | CHS-828 (Nampt inhibitor) prodrug form |
| CAS | 432037-57-5 |
| MW: | 672.6 D |
ab 135,00 €
