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Lenvatinib
Artikelnummer: Cay19375-5
Lenvatinib is an inhibitor of the receptor tyrosine kinases VEGF receptor 2 (VEGFR2) and VEGFR3 (IC50s = 4 and 5.2 nM, respectively). It also inhibits the related kinases VEGFR1, FGFR1, PDGFRalpha, PDGFRbeta and Kit (IC50s = 22, 46, 51, 39, and 100 nM, respectively). Lenvatinib (30 mg/kg, twice per day) reduces...
| Schlagworte: | E-7080, ER-203492-00, 4-[3-chloro-4-[[(cyclopropylamino)carbonyl]amino]phenoxy]-7-methoxy-6-quinolinecarboxamide |
| Anwendung: | VEGFR / FGFR / PDGFR inhibitor |
| CAS | 417716-92-8 |
| MW: | 426.9 D |
ab 43,00 €
E-7080
Artikelnummer: SYN-1038-M001
Soluble in DMSO or ethanol. E7080 is an orally active inhibitor of multiple receptor tyrosine kinases including VEGF, FGF and SCF receptors. It is most potent against VEGFR2(KDR)/VEGFR3(Flt-4), with IC(50) values of 4nM and 5.2nM respectively. Target: FGFR - VEGFR - SCF , Kinase Group: RTK , Substrate: Tyrosine
| Schlagworte: | E-7080 |
| Anwendung: | VEGFR2 /VEGFR3 inhibitor |
| CAS | 417716-92-8 |
| MW: | 426,9 D |
ab 119,00 €
