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PD146176
Artikelnummer: TGM-T7530-100mg
Description: PD146176 (NSC-168807) is an inhibitor of 15-Lipoxygenase (15-LO) , it inhibits rabbit reticulocyte 15-LO with Ki of 197 nM and IC50 of 0.54 µM. PD146176 reverses cognitive impairment, brain amyloidosis, and tau pathology by stimulating autophagy in aged triple transgenic mice. Target: Ferroptosis,...
| Schlagworte: | NSC168807 |
| Anwendung: | 15-LO inhibitor |
| CAS | 4079-26-9 |
| MW: | 237.32 D |
ab 41,00 €
PD 146176
Artikelnummer: Cay10010518-5
PD 146176 is a potent and selective inhibitor of reticulocyte 15-lipoxygenase-1. It limits hypercholesterolemia-induced atherosclerosis in New Zealand White rabbits and reduces oxidant stress-induced apoptosis in endothelial cells. PD 146176 inhibits amyloid beta protein aggregate formation without changing total...
| Schlagworte: | NSC 168807, 6,11-dihydro-[1]benzothiopyrano[4,3-b]indole |
| Anwendung: | 15-LO inhibitor |
| CAS | 4079-26-9 |
| MW: | 237.3 D |
ab 65,00 €
