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NSC 185058
Artikelnummer: TGM-T5211-100mg
Description: NSC 185058, an inhibitor of ATG4B (a major cysteine protease), can also attenuate autophagic activity. Target: Cysteine Protease, Autophagy. Smiles: S=C(Nc1ccccn1)c1ccccn1. References: Akin D, et al. A novel ATG4B antagonist inhibits autophagy and has a negative impact on osteosarcoma tumors....
| Schlagworte: | NSC185058 |
| Anwendung: | ATG4B inhibitor |
| CAS | 39122-38-8 |
| MW: | 215.27 D |
ab 59,00 €
NSC 185058
Artikelnummer: Cay23957-5
NSC 185058 is an inhibitor of ATG4B, a cysteine protease that activates LC3B during the initiation of autophagy. It inhibits ATG4B cleavage of LC3B-GST (IC50 = 51 µM) and reduces LC3B lipidation induced by starvation in Saos-2 cells. NSC 185058 (100 µM) reduces starvation-induced autophagy and prevents autophagic...
| Schlagworte: | N-2-pyridinyl-2-pyridinecarbothioamide |
| Anwendung: | ATG4B inhibitor |
| CAS | 39122-38-8 |
| MW: | 215.3 D |
ab 77,00 €
