Zu "387867-13-2" wurden 5 Artikel gefunden!
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Tandutinib
Artikelnummer: TGM-T1667-100mg
Description: Tandutinib (CT53518) (MLN518, CT53518), an effective FLT3 antagonist (IC50: 0.22 µM), can also inhibit c-Kit and PDGFR, 15-20 fold higher potency for FLT3 versus CSF-1R and >100-fold selectivity for the same target versus FGFR, EGFR, and KDR. Target: c-Kit, CSF-1R, Src, FLT, PDGFR, Apoptosis....
| Schlagworte: | NSC726292, CT53518, MLN518 |
| Anwendung: | Targets fms-related tyrosine kinase 3 [EC:2.7.10.1] (FLT3, FLK2, CD135) |
| CAS | 387867-13-2 |
| MW: | 562.7 D |
ab 40,00 €
Tandutinib
Artikelnummer: Cay12098-100
Tandutinib is a potent antagonist of platelet-derived growth factor receptor beta (PDGFRbeta), FLT3, and c-Kit (IC50 = 200, 220, and 170 nM, respectively). It less potently inhibits macrophage colony-stimulating factor 1 receptor (IC50 = 3.4 µM) and does not significantly inhibit other tyrosine or serine/threonine...
| Schlagworte: | CT 53518, MLN518,... |
| Anwendung: | PDGFR-beta / Flt3 / c-Kit antagonist |
| CAS | 387867-13-2 |
| MW: | 562.7 D |
ab 77,00 €
![Tandutinib, Free Base (4-[6-methoxy-7-[3-(1-piperidinyl)propoxy]-4-quinazolinyl]-N-[4-(1-methylethox](https://www.biomol.com/media/image/28/87/a5/T0895-50-25_200x200.jpg "Tandutinib, Free Base (4-[6-methoxy-7-[3-(1-piperidinyl)propoxy]-4-quinazolinyl]-N-[4-(1-methylethox")
Tandutinib, Free Base...
Artikelnummer: T0895-50.25
Tandutinib (also known as MLN518 or CT53518) is an orally active inhibitor of Fms-like tyrosine kinase 3 (FLT3) kinase, PDGFRb and c-Kit. It inhibits FLT3 phosphorylation, downstream signaling and tumor growth in vitro and in animal models. Solubility: Soluble in DMSO at 25mg/ml with slight warming, soluble in...
| CAS | 387867-13-2 |
| MW: | 562.70 |
214,00 €
Tandutinib
Artikelnummer: LKT-T0152.1
A piperazinyl quinazoline receptor tyrosine kinase inhibitor with antineoplastic activity. Tandutinib inhibits the autophosphorylation of FLT3 (FMS-Like Tyrosine kinase-3), c-KIT and PDGF (platelet-derived growth factor) receptor tyrosine kinases.
| CAS | 387867-13-2 |
| MW: | 562,7 D |
ab 146,00 €
Tandutinib
Artikelnummer: SYN-1088-M001
Soluble in DMSO or ethanol. Tandutinib inhibits the auto-phosphorylation of FLT3 (FMS-Like Tyrosine kinase-3, IC(50) of 0.22µM), c-KIT and PDGF (platelet-derived growth factor), thereby inhibiting cellular proliferation and inducing apoptosis. Target: PDGFR , Kinase Group: RTK , Substrate: Tyrosine
| Schlagworte: | CT53518, MLN518 |
| Anwendung: | FLT3 / PDGFR /c-KIT inhibitor |
| CAS | 387867-13-2 |
| MW: | 562,7 D |
ab 77,00 €
