Zu "383150-41-2" wurden 2 Artikel gefunden!
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JTE-013
Artikelnummer: Cay10009458-10
JTE-013 is a sphingosine-1-phosphate receptor 2 (S1P2) and S1P4 antagonist (IC50s = 17 and 237 nM, respectively). It is selective for S1P2 over S1P1 and S1P3 (IC50s = >10 µM for both). JTE-013 (1 and 10 µM) reverses S1P-induced inhibition of human umbilical vein endothelial cell (HUVEC) and smooth muscle cell (SMC)...
| Schlagworte: | N-(2,6-dichloro-4-pyridinyl)-2-[1,3-dimethyl-4-(1-methylethyl)-1H-pyrazolo[3,4-b]pyridin-6-yl]-hydrazinecarboxamide |
| Anwendung: | S1P2 receptor antagonist |
| CAS | 383150-41-2 |
| MW: | 408.3 D |
ab 36,00 €
JTE-013
Artikelnummer: TGM-T15629-10mg
Description: JTE-013 is an effective and specific antagonist of S1P2. JTE-013 suppresses the specific binding of radiolabeled S1P to human and rat S1P2 (IC50s: 17 nM and 22 nM, respectively). Target: S1P Receptor, Apoptosis, LPL Receptor. Smiles: CC(C)c1cc(NNC(=O)Nc2cc(Cl)nc(Cl)c2)nc2n(C)nc(C)c12. References: Li...
| CAS | 383150-41-2 |
| MW: | 408.29 D |
ab 71,00 €
