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Saracatinib
Artikelnummer: Cay11497-5
Saracatinib is a dual inhibitor of the tyrosine kinases c-Src and Abl (IC50 = 2.7 and 30 nM, respectively). It less effectively inhibits other receptor and non-receptor tyrosine kinases as well as assorted serine/threonine kinases. Saracatinib is orally available and blocks cell motility, migration, adhesion,...
| Schlagworte: | AZD 0530,... |
| Anwendung: | c-Src / Abl inhibitor |
| CAS | 379231-04-6 |
| MW: | 542 D |
ab 42,00 €
![Saracatinib, Free Base (N-(5-chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]-5-(ox](https://www.biomol.com/media/image/c3/9d/7b/S0097-50-10_200x200.jpg "Saracatinib, Free Base (N-(5-chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]-5-(ox")
Saracatinib, Free Base...
Artikelnummer: S0097-50.10
Saracatinib an orally available Src kinase inhibitor. Saracatinib inhibits c-Src and Abl enzymes at low nanomolar concentrations. Saracatinib blocked the tumor growth of a c-Src-transfected 3T3-fibroblast xenograft in vivo and increased significantly the survival of animals in a highly aggressive model of human...
| CAS | 379231-04-6 |
| MW: | 542.03 |
230,00 €
