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CAY10602
Artikelnummer: TGM-T4062-100mg
Description: CAY10602 is a SIRT1 activator derived from high throughput screening for compounds that enhance SIRT1-mediated deacetylation of a SIRT1-specific substrate. Functional assays indicate that CAY10602 dose-dependently suppresses NF-kappaB-dependent induction of TNF-alpha by lipopolysaccharide in THP-1...
| Anwendung: | SIRT1 activator |
| CAS | 374922-43-7 |
| MW: | 418.44 D |
ab 47,00 €
CAY10602
Artikelnummer: Cay10009796-5
CAY10602 is an activator of sirtuin 1 (SIRT1). It inhibits LPS-induced TNF-alpha release in THP-1 cells when used at concentrations of 20 and 60 µM. CAY10602 (5 µM) decreases the expression of GPX4, SLC7A11, and SLC3A2, as well as increases the levels of iron and malondialdehyde (MDA), in A549 lung and MDA-MB-231...
| Schlagworte: | 1-(4-fluorophenyl)-3-(phenylsulfonyl)-1H-pyrrolo[2,3-b]quinoxalin-2-amine |
| Anwendung: | SIRT1 activator |
| CAS | 374922-43-7 |
| MW: | 418.4 D |
ab 40,00 €
