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TMPyP4 tosylate
Artikelnummer: TGM-T13174-100mg
Description: TMPyP4 tosylate (TMP 1363) is a quadruplex-specific ligand and telomerase inhibitor that exhibits antitumor effects in osteosarcoma cell lines. Target: DNA/RNA Synthesis, Telomerase. Smiles:...
| Schlagworte: | TMP 1363 |
| Anwendung: | G-quadruplex stabilizer, telomerase inhibitor |
| CAS | 36951-72-1 |
| MW: | 1363.6 D |
ab 35,00 €
TMPyP4 (tosylate)
Artikelnummer: Cay18474-50
TMPyP4 is a cationic porphyrin that intercalates into and stabilizes G-quadruplexes, which are formed by DNA and RNA sequences composed of blocks of guanine residues. In this way, TMPyP4 inhibits telomerase activity (IC50 = 50 µM), blocking the clonogenic growth and migration of cancer cells in culture and in vivo....
| Schlagworte: | TMP-1363, TMPyP4 4-methylbenzenesulfonate,... |
| Anwendung: | G-quadruplex stabilizer, Telomerase inhibitor |
| CAS | 36951-72-1 |
| MW: | 1363.6 D |
ab 52,00 €
