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GP-82996
Artikelnummer: TGM-T21720-100mg
Description: GP-82996 (CINK4) is a pharmacological inhibitor specifically targeting CDK4/6, exhibiting IC50 values of 1.5 µM for CDK4/cyclin D1, 5.6 µM for CDK6/cyclin D1, and 25 µM for Cdk5/p35. It effectively induces apoptosis in U2OS cancer cells, positioning it as a potential investigational tool in cancer...
| Schlagworte: | Cdk4/6 Inhibitor IV, CINK4 |
| CAS | 359886-84-3 |
| MW: | 456.58 D |
ab 48,00 €
Cdk4/6 Inhibitor IV
Artikelnummer: Cay17974-1
Cdk4/6 inhibitor IV is a cell-permeable triaminopyrimidine that reversibly blocks Cdk4/cyclin D1 and Cdk6/cyclin D1 activity with IC50 values of 1.5 and 5.6 µM, respectively. It demonstrates potent selectivity for Cdk4/6 over Cdk5/p35, v-abl, c-met, IGF-1R, insulin receptor, Cdk2/cyclin A, Cdk2/cyclin E, Cdk4/cyclin...
| Schlagworte: | CINK4, Cyclin-dependent kinase 4/6 Inhibitor IV,... |
| Anwendung: | Cdk4/cyclin D1 inhibitor, Cdk6/cyclin D1 inhibitor |
| CAS | 359886-84-3 |
| MW: | 456.6 D |
ab 59,00 €
