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Balicatib
Artikelnummer: TGM-T1850-100mg
Description: Balicatib (AAE581) is a potent and selective inhibitor of cathepsin K, used in trials studying the treatment of osteoporosis. Target: Cysteine Protease. Smiles: CCCN1CCN(CC1)c1ccc(cc1)C(=O)NC1(CCCCC1)C(=O)NCC#N. References: Jerome C, et al. Osteoporos Int. 2012 Jan,23(1):339-49.
| Schlagworte: | AAE581 |
| Anwendung: | Cathepsin K inhibitor |
| CAS | 354813-19-7 |
| MW: | 411.54 D |
ab 37,00 €
Balicatib
Artikelnummer: Cay17995-10
Balicatib is a potent inhibitor of cathepsin K (IC50s = 1.4, 56, and 480 nM for human, rat, and mouse forms, respectively). it is at least 100-fold selective for cathepsin K over cathepsins B, L, and S. Balicatib has a basic lipophilic nature, resulting in lysosomal trapping and increased selectivity for lysosomal...
| Schlagworte: | AAE581, N-[1-[[(cyanomethyl)amino]carbonyl]cyclohexyl]-4-(4-propyl-1-piperazinyl)-benzamide |
| Anwendung: | Cathepsin K inhibitor |
| CAS | 354813-19-7 |
| MW: | 411.5 D |
ab 111,00 €
Balicatib
Artikelnummer: LKT-B0245.25
Cathepsin K inhibitor.
| Schlagworte: | AAE-581 |
| Anwendung: | Cathepsin K inhibitor |
| CAS | 354813-19-7 |
| MW: | 411.55 D |
ab 199,00 €
