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NS6180
Artikelnummer: TGM-T1752-100mg
Description: NS6180 is a potent and selective KCa3.1 channel inhibitor(IC50= 9 nM). It prevents T-cell activation and inflammation. Target: Potassium Channel. Smiles: FC(F)(F)c1cccc(CN2C(=O)CSc3ccccc23)c1. References: Strobak D, et al. Br J Pharmacol. 2013 Jan,168(2):432-44.
| Anwendung: | KCa3.1 channel blocker |
| CAS | 353262-04-1 |
| MW: | 323.33 D |
ab 33,00 €
NS 6180
Artikelnummer: Cay14664-10
NS 6180 is an inhibitor of the intermediate-conductance calcium-activated potassium channel 3.1 (IKCa1/KCa3.1, IC50 = 9.4 nM in HEK293 cells expressing the human channel). It inhibits hyperpolarization of human, mouse, and rat erythrocytes induced by the calcium ionophore A23187 (Cay-11016) (IC50s = 14, 15, and 9...
| Schlagworte: | 4-[[3-(trifluoromethyl)phenyl]methyl]-2H-1,4-benzothiazin-3(4H)-one |
| Anwendung: | KCa3.1 channel blocker |
| CAS | 353262-04-1 |
| MW: | 323.3 D |
ab 111,00 €
