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Necrostatin-5
Artikelnummer: TGM-T37558-10mg
Description: Necrostatin-5 (Nec-5) is a selective RIP1 kinase inhibitor and cell necrosis inhibitor that prevents the death of Fadd-deficient Jurkat cells treated with TNF-alpha, with an EC50 of 240 nM. Target: Necroptosis, RIP kinase. Smiles: O=C1C=2C3=C(SC2N=C(SCC#N)N1C4=CC=C(OC)C=C4)CCCC3. References:...
| Schlagworte: | Nec-5 |
| Anwendung: | Necroptosis inhibitor |
| CAS | 337349-54-9 |
| MW: | 383.49 D |
ab 38,00 €
Necrostatin-5
Artikelnummer: Cay10527-5
Necrostatin-5 is a RIP1 kinase inhibitor. It inhibits phosphorylation of RIP1 in Jurkat cells when used at concentrations of 10 and 30 µM. Necrostatin-5 inhibits TNF-alpha-induced necroptosis in Jurkat cells deficient in Fas-associated death domain protein (FADD, EC50 = 0.24 µM), a modification that prevents caspase...
| Schlagworte: | Nec-5, 2-[[3,4,5,6,7,8-hexahydro-3-(4-methoxyphenyl)-4-oxo[1]benzothieno[2,3-d]pyrimidin-2-yl]thio]-acetonitrile |
| Anwendung: | RIP1 kinase inhibitor |
| CAS | 337349-54-9 |
| MW: | 383.5 D |
ab 66,00 €
Necrostatin-5
Artikelnummer: AG-CR1-0049-M005
Necroptosis inhibitor, Indirect RIP1 kinase inhibitor.
| Schlagworte: | Nec-5, 3-p-Methoxyphenyl-5,6-tetramethylenothieno[2,3-d]pyrimidin-4-one-2-mercaptoethylcyanide |
| Anwendung: | Necroptosis inhibitor |
| CAS | 337349-54-9 |
| MW: | 383,5 D |
ab 44,00 €
