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Betrixaban
Artikelnummer: TGM-T4341-100mg
Description: Betrixaban (PRT054021) is a non-vitamin K oral anticoagulant whose action is driven by the competitive and reversible inhibition of the factor Xa [1]. It was selected among all lead compounds due to its low hERG channel affinity while sustaining its factor Xa inhibition capacity [3]. Betrixaban, now...
| Schlagworte: | PRT054021 |
| Anwendung: | Targets coagulation factor X [EC:3.4.21.6] (F10) |
| CAS | 330942-05-7 |
| MW: | 451.91 D |
ab 41,00 €
Betrixaban
Artikelnummer: Cay21563-100
Betrixaban is an inhibitor of the serine protease Factor Xa (Ki = 0.117 nM, IC50 = 1.5 nM), the enzyme that activates prothrombin in the blood coagulation cascade. It is selective for Factor Xa over hERG channels (Ki = 1.8 µM, IC50 = 8.9 µM), indicating a low potential for adverse cardiac effects. In vitro,...
| Schlagworte: | MK-4448, MLN1021, PRT054021, N-(5-chloro-2-pyridinyl)-2-[[4-[(dimethylamino)iminomethyl]benzoyl]amino]-5-methoxy-benzamide |
| Anwendung: | Factor Xa inhibitor |
| CAS | 330942-05-7 |
| MW: | 451.9 D |
ab 300,00 €
