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PCI 29732
Artikelnummer: TGM-T4337-100mg
Description: PCI 29732 is a selective and irreversible Btk inhibitor with IC50 of 8.2 nM in a FRET based biochemical enzymology assay. Target: BTK, BCRP, Others. Smiles: Nc1ncnc2n(nc(-c3ccc(Oc4ccccc4)cc3)c12)C1CCCC1. References: Pan Z, etal. Discovery of selective irreversible inhibitors for Bruton's tyrosine...
| Schlagworte: | PCI29732, PCI-29732 |
| Anwendung: | Multi-kinase inhibitor |
| CAS | 330786-25-9 |
| MW: | 371.43 D |
ab 34,00 €
PCI-29732
Artikelnummer: Cay29036-1
PCI-29732 is a multi-kinase inhibitor. It inhibits the Tec family kinase BTK and the Src family kinases LCK and LYN (Kis = 8.2, 4.6, and 2.5 nM, respectively), as well as the activity of three receptor tyrosine kinases and seven non-receptor tyrosine kinases by greater than 90% in a panel of over 100 kinases at 10...
| Schlagworte: | 1-cyclopentyl-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine |
| Anwendung: | Multi-kinase inhibitor |
| CAS | 330786-25-9 |
| MW: | 371.4 D |
ab 43,00 €
