Zu "328998-53-4" wurden 2 Artikel gefunden!
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inS3-54A18
Artikelnummer: TGM-T15582-100mg
Description: inS3-54A18 is an effective inhibitor of STAT3. inS3-54A18 has anticancer effects. Target: STAT. Smiles: Oc1ccc(cc1)N1C(=O)\C(=C/c2ccc(Cl)cc2)C=C1c1ccccc1. References: Huang W, et al. Small-molecule inhibitors targeting the DNA-binding domain of STAT3 suppress tumor growth, metastasis and STAT3 target...
| Anwendung: | STAT3 inhibitor |
| CAS | 328998-53-4 |
| MW: | 373.83 D |
ab 42,00 €
inS3-54-A18
Artikelnummer: Cay39678-1
inS3-54-A18 is an inhibitor of STAT3. It selectively inhibits the binding of STAT3 to DNA over STAT1 at 25 µM. inS3-54-A18 (20 µM) inhibits STAT3 activity in a reporter assay using MDA-MB-231 breast cancer cells. It induces apoptosis in, and reduces migration and invasion of, A549 non-small cell lung cancer (NSCLC)...
| Schlagworte: | 3-[(4-chlorophenyl)methylene]-1,3-dihydro-1-(4-hydroxyphenyl)-5-phenyl-2H-pyrrol-2-one |
| Anwendung: | STAT3 inhibitor |
| CAS | 328998-53-4 |
| MW: | 373.8 D |
ab 66,00 €
