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TCS-PIM-1-4a
Artikelnummer: TGM-T4215-100mg
Description: TCS-PIM-1-4a (SMI-4a), a Pim inhibitor, blocks mTORC1 activity through activation of AMPK and kills a wide range of both myeloid and lymphoid cell lines (IC50=0.8-40 µM). Target: Pim, Apoptosis. Smiles: C(=C1SC(=O)NC1=O)C2=CC(C(F)(F)F)=CC=C2. References: Lin YW, et al. A small molecule inhibitor of Pim...
| Schlagworte: | SMI-4a |
| Anwendung: | Pim-1/Pim-2 kinase inhibitor |
| CAS | 327033-36-3 |
| MW: | 273.23 D |
ab 46,00 €
SMI-4a
Artikelnummer: AG-CR1-3503-M005
Selective inhibitor of Pim-1 and Pim-2 protein kinases, Inducer of G1 phase cell cycle arrest, Inducer of p27Kip1, Inducer of apoptosis through the mitochondrial pathway, Inhibitor of the mammalian target of rapamycin C1 (mTORC1) pathway, Downregulates c-myc, Inhibitor of PRAS40 phosphorylation and mTOR activity,...
| Schlagworte: | (5E/Z)-[[3-(Trifluoromethyl)phenyl]methylene]-2,4-thiazolidinedione |
| Anwendung: | Pim-1/Pim-2 kinase inhibitor |
| CAS | 327033-36-3 |
| MW: | 273,2 D |
88,00 €
